Hodgkin Huxley Neuron Models

• Hodgkin and Huxley got the Nobel prize in Physiology in 1963 largely for the work on this model.
• Unlike point models, the Hodgkin Huxley model is based on gates and channels.
• This accounts for the way a spike works.
• Of course the model is not the reason they got the prize, but the under lying mathematics, the idea of channels, and the alignment to biology.
• In the 50s and 60s proposing a mathematically solid model of aspects of a neuron was extermely important.
• Currently, a lot of relatively sophisticated models use this channel and gating mechanism to account for the behaviour of neurons via neurotransmitters.